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David B Huang Selected Research

Vancomycin

4/2020A pooled analysis of patients with wound infections in the Phase 3 REVIVE trials: randomized, double-blind studies to evaluate the safety and efficacy of iclaprim versus vancomycin for treatment of acute bacterial skin and skin structure infections.
3/2020A Multicenter Evaluation of Vancomycin-Associated Acute Kidney Injury in Hospitalized Patients with Acute Bacterial Skin and Skin Structure Infections.
1/2020Effect of Vancomycin-Associated Acute Kidney Injury on Incidence of 30-Day Readmissions among Hospitalized Veterans Affairs Patients with Skin and Skin Structure Infections.
3/2019The effects of iclaprim on exotoxin production in methicillin-resistant and vancomycin-intermediate Staphylococcus aureus.
2/2019Iclaprim activity against wild-type and corresponding thymidine kinase-deficient Staphylococcus aureus in a mouse protection model.
1/2019A Pooled Analysis of the Safety and Efficacy of Iclaprim Versus Vancomycin for the Treatment of Acute Bacterial Skin and Skin Structure Infections in Patients With Intravenous Drug Use: Phase 3 REVIVE Studies.
8/2018Pooled analysis of the phase 3 REVIVE trials: randomised, double-blind studies to evaluate the safety and efficacy of iclaprim versus vancomycin for treatment of acute bacterial skin and skin-structure infections.
4/2018Efficacy evaluation of iclaprim in a neutropenic rat lung infection model with methicillin-resistant Staphylococcus aureus entrapped in alginate microspheres.
2/2018An Updated Review of Iclaprim: A Potent and Rapidly Bactericidal Antibiotic for the Treatment of Skin and Skin Structure Infections and Nosocomial Pneumonia Caused by Gram-Positive Including Multidrug-Resistant Bacteria.
1/2018A Phase 3, Randomized, Double-Blind, Multicenter Study To Evaluate the Safety and Efficacy of Intravenous Iclaprim versus Vancomycin for Treatment of Acute Bacterial Skin and Skin Structure Infections Suspected or Confirmed To Be Due to Gram-Positive Pathogens (REVIVE-2 Study).
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David B Huang Research Topics

Disease

44Infections
01/2022 - 11/2003
9Diarrhea
04/2020 - 11/2003
5Healthcare-Associated Pneumonia
02/2018 - 12/2010
4Virus Diseases (Viral Diseases)
04/2005 - 11/2004
3Acute Kidney Injury (Acute Renal Failure)
03/2020 - 11/2018
3Septic Shock (Toxic Shock Syndrome)
03/2019 - 06/2012
3Bacteremia
05/2014 - 12/2010
3Inflammation (Inflammations)
11/2011 - 02/2004
2Bacterial Pneumonia
02/2018 - 01/2017
2Pneumonia (Pneumonitis)
01/2018 - 12/2010
2Body Weight (Weight, Body)
01/2018 - 01/2018
2Neoplasms (Cancer)
01/2005 - 01/2004
2Communicable Diseases (Infectious Diseases)
10/2004 - 04/2004
2Mycoses (Diseases, Fungus)
01/2004 - 01/2004
1Chills
01/2022
1Cough
01/2022
1Fever (Fevers)
01/2022
1Headache (Headaches)
01/2022
1Rhinorrhea
01/2022
1Toxoplasmosis
04/2021
1Endocarditis
01/2021
1Sepsis (Septicemia)
01/2021
1Wound Infection (Wound Infections)
04/2020
1Fatigue
04/2020
1Chronic Kidney Failure (Chronic Renal Failure)
03/2020
1Cellulitis
03/2020
1Alcoholism (Alcohol Abuse)
03/2020
1Cystic Fibrosis (Mucoviscidosis)
12/2019
1Staphylococcal Infections
03/2019
1Abscess
01/2019
1Hyperkalemia
11/2018
1Obesity
10/2013
1Bacterial Infections (Bacterial Infection)
06/2013
1Cerebrovascular Disorders (Cerebrovascular Occlusion)
06/2013
1Dementia (Dementias)
06/2013
1Vascular Diseases (Vascular Disease)
06/2012
1Thrombocytopenia (Thrombopenia)
06/2012
1Irritable Bowel Syndrome (Syndrome, Irritable Bowel)
01/2012
1Necrosis
04/2009
1Carcinoma (Carcinomatosis)
01/2009
1Typhoid Fever (Typhoid)
06/2005

Drug/Important Bio-Agent (IBA)

24iclaprim (AR 100)IBA
04/2021 - 01/2017
21VancomycinFDA LinkGeneric
04/2020 - 09/2010
12Anti-Bacterial Agents (Antibiotics)IBA
01/2022 - 01/2004
11Linezolid (Zyvox)FDA Link
02/2018 - 09/2010
6Rifaximin (L 105)FDA Link
01/2012 - 02/2004
4Anti-Infective Agents (Microbicides)IBA
12/2019 - 08/2004
4Folic Acid AntagonistsIBA
01/2019 - 01/2017
4Antiviral Agents (Antivirals)IBA
04/2005 - 10/2004
3DaptomycinFDA Link
01/2021 - 05/2014
3Panton-Valentine leukocidinIBA
03/2019 - 06/2012
3Trimethoprim (Proloprim)FDA LinkGeneric
03/2019 - 11/2018
3Interleukin-8 (Interleukin 8)IBA
04/2009 - 02/2004
3CytokinesIBA
01/2005 - 02/2004
2Hemolysin Proteins (Hemolysins)IBA
11/2018 - 06/2012
2VaccinesIBA
04/2005 - 04/2004
2NucleosidesIBA
11/2004 - 11/2004
2Virulence Factors (Pathogenicity Factors)IBA
05/2004 - 11/2003
1C-Reactive ProteinIBA
01/2022
1dihydrofolateIBA
04/2021
1beta-LactamsIBA
03/2020
1LactamsIBA
12/2019
1tazobactam drug combination ceftolozaneIBA
12/2019
1meropenem and vaborbactamIBA
12/2019
1Tazobactam Drug Combination Piperacillin (Zosyn)FDA LinkGeneric
12/2019
1ceftazidime drug combination avibactamIBA
12/2019
1Proteins (Proteins, Gene)FDA Link
03/2019
1scorpion toxin I''IBA
03/2019
1Folic Acid (Vitamin M)FDA LinkGeneric
03/2019
1NafcillinFDA LinkGeneric
03/2019
1Thymidine KinaseIBA
01/2019
1CytodexIBA
01/2019
1SulfonamidesIBA
11/2018
1ExotoxinsIBA
11/2018
1AlginatesIBA
04/2018
1Dihydrotachysterol (AT 10)IBA
02/2018
1exebacaseIBA
05/2014
1Carbapenems (Carbapenem Antibiotics)IBA
03/2014
1AntigensIBA
06/2013
1CoagulaseIBA
06/2012
1Phenol (Carbolic Acid)FDA Link
06/2012
1Staphylococcal Protein A (Protein A)IBA
06/2012
1Enterotoxins (Enterotoxin)IBA
06/2012
1Serotonin AgentsIBA
02/2012
1Serotonin (5 Hydroxytryptamine)IBA
02/2012
1Polymyxins (Polymyxin)IBA
01/2011
1Polymyxin B (Aerosporin)FDA LinkGeneric
01/2011
1InterleukinsIBA
04/2009
1Interleukin-6 (Interleukin 6)IBA
04/2009
1Loperamide (Imodium)FDA LinkGeneric
04/2007
1FluoroquinolonesIBA
06/2005
1Third Generation CephalosporinsIBA
06/2005

Therapy/Procedure

13Therapeutics
01/2021 - 03/2002
1Renal Replacement Therapy (Therapies, Renal Replacement)
03/2020
1Microspheres (Microsphere)
04/2018
1Mechanical Ventilators (Ventilator)
02/2018
1Home Nursing (Nursing, Home)
06/2013
1Catheters
06/2012
1Chemoprevention
01/2009
1Intravesical Administration
01/2009